Novel KIT Missense Mutation P665S in a Chinese Piebaldism Family
نویسندگان
چکیده
Vol. 29, No. 6, 2017 801 Received July 27, 2016, Revised October 10, 2016, Accepted for publication October 31, 2016 Corresponding author: Yanhua Liang, Department of Dermatology, Shenzhen Hospital of Southern Medical University, 1333 Xinhu Road, Shenzhen, Guangdong 518100, China. Tel: 86-755-23360448, Fax: 86-755-23360448, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology shorter than pressure ulcer and all ulcers with SGD patients were healed completely. As elderly people gradually increase worldwide, it is important that these ulcers should be recognized in SGD patients and distinguished from pressure ulcer. In conclusion, the ulcers developed with SGD are thought to be produced by mainly friction more than pressure force in elderly peoples, and their locations different from that of pressure ulcers. And it is important to notice that these SGD ulcers have relatively shorter duration and better response of treatment than that of pressure ulcers, so it is necessary to avoid excessive treatment.
منابع مشابه
A novel missense KIT mutation causing piebaldism in one Chinese family associated with café-au-lait macules and intertriginous freckling
Piebaldism is a rare autosomal dominant genodermatosis, manifesting as congenital and stable depigmentation of the skin and white forelock. It has been found to be associated with mutations in the KIT or SLUG genes. We report a Chinese piebaldism family including a 28-year-old woman and her 3-year-old son with characteristics of white patches and forelock associated with numerous brown macules ...
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